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KMID : 0352519940310010073
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Korea Univercity Medical Journal
1994 Volume.31 No. 1 p.73 ~ p.88
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Seroepidemiologic Study of Hemorrhagic fever with Renal Syndrome, Scrb typhus, Murine Typhus, Spotted Fever and Leptospirosis in Korea, 1991
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이광래
백락주/송기준/우영대/이용주/이호왕
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Abstract
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Acute febrile hemorrhagic diseases that occurred in Korea have been confirmed as Hemorrhagic fever with renal syndrome (HFRS), scrub typhus, murine typhus, Spotted fever and Leptospirosis. We accumulated 2,679 sera from patients who
showed
symptoms of Acute febrile hemorrhagic diseases during the etiologic agents of Hemorrhagic fever with renal syndrome, Scrub typhus. Murine typhus, Spotted fever and Leptospirosis, then analysed their seroepidemiologic characteristics.
@ES The results were as follows:
@EN 1. Of 1,234 serologically confirmed HFRS cases during the year of 1991 in Korea, 374 cases were confirmed at the Institute for Viral Diseases, Korea University, 432 cases at Seoul Nat'l University Colleage of Medicine, 150 cases at NIH,
Republic
of Korea and 278 cases at Korea Green Cross Hospital.
2. Of 2,679 sera from acute febrile hemorrhagic disease patients tested in 1991, 374 cases of HFRS, 150 cases of Murine typhus, 377 cases of Scrub typhus, 10 cases of Spotted fever and 15 cases of Leptospirosis were confirmed serologically.
3. Analysis of geographic distribution of acute febrile hemorrhagic disease patients revealed that the majority of HFRS patients occurred in Kyunggi-do, Seoul city, Chungcheongnam-do and Jeollanam-do and murine typhus occurred mostly
in
Seoul city, Kyunggi-do and Chungcheongnam-do and Scrub typhus occurred mostly in Seoul city, Kyunggi-do, Chungcheongnam-do and Jeollabuk-do and 8 cases of Spoted fever confirmed in Seoul city and Chungcheongnam-do and few
Leptospirosis
patients occurred in Seoul city, Kyunggi-do and Kangwon-do
4. Seasonal and monthly incidence of acute febrile hemorrhagic diseases indicated that HFRS in civilian population had two seasonal peaks, summer and fall but, in military persons one seasonal peak, fall and Murine typhus occurred
mostly
between July and December and Scrub typhus occurred mostly in October and December and Spotted fever and Leptospirosis occurred only in summer.
5. Sex distribution of acute febrile hemorrhagic diseases showed that HFRS occurred mainly in male and the incidence of male was twice as much as that of female and Murine typhus also occurred mainly in male and Scrub typhus occurred in
female
but
incidence of female to male was nearly same and Spotted fever and Leptospirosis occurred mostly in male.
6. Age distribution of acute febrile hemorrhagic diseases showed that HFRS occurred mainly in adult and Scrub typhus occurred in all age groups, but, occurred especially in older age groups between 40 year old and 80 year old age and
Spotted
fever and Leptospirosis occurred chiefly in adult.
7. In 1991, 44 HFRS patients occurred between October and December, but, there was no incidence of HFRS in summer in Korean Army. Only 1 Scrub typhus and 1 Murine typhus patients occurred in Korean Army.
Above results revealed that HFRS, murine typhus, scrub typhus, spotted fever and
leptospirosis patients occurred throughout the year in Korea but, the fact that about 60% of clinical cases of acute febrile hemorrhagic diseases patients were still not diagnosed serologically revealed that another diseases will be
exist.
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KEYWORD
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